With the prohibition era nearing its end, it is imperative to begin discussing how to shape an effective, comprehensive cannabis regulatory framework. The system proposed in our white paper would allow all cannabis products to flow to the market through a regulatory scheme designed to best advance the policy goals raised by these products. It builds off the existing expertise of federal agencies and the developing state-level industry. Potentially intoxicating products and those making medical claims will be sold through controlled systems that limit their availability, while non-intoxicating products will not be hampered by those same restrictions. Our proposed system would end prohibition in a thoughtful and comprehensive manner, ensuring that the mistakes of the previous era do not negatively affect the opportunities that are at our doorstep.