President Obama lost his mandate to govern Tuesday, as his party ceded control of the Senate and additional seats in the House. For partisans who obsess over the ups and downs of every election cycle, that makes Democrats seem like the biggest losers in the midterms, though they could realistically regain the Senate in 2016.

Indisputably, the Democrats had a terrible night.

But the 2014 losers least likely to regain ground in future elections are marijuana prohibitionists. Oregon and Alaska just became the third and fourth states to legalize the drug. Washington, D.C., voted for legalization, as did the city of South Portland, Maine. The island territory of Guam chose to allow medicinal marijuana. And while Florida voters defeated a constitutional amendment legalizing medicinal weed, it required 60 percent support to pass and received roughly 58 percent of the vote. A healthy majority in the state want medical cannabis to be legal.

Read more: The Other Big Election 2014 Losers: Marijuana Prohibitionists | The Atlantic